Another treatment possibility is removal of the uterus, also known as hysterectomy. Persistent GTN is usually treated with chemotherapy. In some cases, the mole that causes the molar pregnancy goes deep into the middle layer of the uterine wall. One sign of persistent GTN is a high level of human chorionic gonadotropin (HCG) - a pregnancy hormone - after the molar pregnancy has been removed. GTN happens more often in complete molar pregnancies than it does in partial molar pregnancies. This is called persistent gestational trophoblastic neoplasia (GTN). A molar pregnancy is more likely in people older than age 43 or younger than age 15.Īfter removing a molar pregnancy, molar tissue might remain and continue to grow. A repeat molar pregnancy happens, on average, in 1 out of every 100 people. If you've had one molar pregnancy, you're more likely to have another. Risk factorsįactors that can contribute to a molar pregnancy include: This most often occurs when two sperm fertilize an egg, resulting in an extra copy of the father's genes. The embryo then has 69 chromosomes instead of 46. In a partial or incomplete molar pregnancy, the mother's chromosomes are present, but the father supplies two sets of chromosomes. The chromosomes from the mother's egg are missing or don't work. In a complete molar pregnancy, one or two sperm fertilize an egg. In a typical fertilization, one chromosome in each pair comes from the father, the other from the mother. Human cells usually have 23 pairs of chromosomes. An egg fertilized atypically causes a molar pregnancy.
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